Metabolism in Disease & Therapeutic Targeting

Many chronic diseases are characterized by persistent alterations in nutrient signaling and metabolic state. Our research examines how dysregulated metabolic pathways contribute toconditions such as obesity, type 2 diabetes, cardiometabolic disease, polycystic kidney disease, and cancer.

By identifying key regulatory nodes that govern metabolic function, we aim to develop therapeutic strategies to reprogram metabolism by restoring tissue function and improving systemic health without disrupting essential physiological processes. 

Cancer Metabolism

Translational Goals:

Identify actionalble targets

Develop therapeutic strategies

Combine metabolic and endocrine intervention

(above) Prostate cancer cells invading the surrounding stroma