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About
About

Located at the University of Massachusetts Chan Medical School in Worcester, MA, the Department of Molecular, Cell & Cancer Biology is a collaborative group dedicated to translating fundamental discoveries in biomedical research into novel therapeutic strategies for cancer and other diseases.
Faculty
Faculty

Our faculty make innovative, high-impact discoveries in biomedical research in molecular, cell and cancer biology.
Research
Research

Explore how our bold discoveries are redefining our understanding of how diseases start and can be treated.
Bioinformatics Core
Bioinformatics Core

The MCCB Bioinformatics Core is a unique in-house resource that provides cutting-edge bioinformatics and biostatistics support to researchers in the department.
Education
Education

MCCB is dedicated to fostering innovation and training the next generation of scientists. Learn more about how MCCB equips students and early-career researchers with the skills and knowledge to drive scientific discovery.
- Postdoctoral Training
  
  Postdoctoral Training
  
  Educational Enrichment Activities
  
  Professional Development & Support
  
  MCCB Postdoc Achievements
- Graduate Training
  
  Graduate Programs
  
  Educational Enrichment Activities
  
  Professional Development & Support
  
  Current MCCB Students
  
  MCCB Student Achievements
  
  Michael R. Green, MD, PhD, Award in Graduate Research
  
  MCCB Faculty Awards in Education
Support Us
Support Us

Learn more about how you can support MCCB’s fundraising initiatives to advance research at UMass Chan.
- Michael R. Green, MD, PhD, Award in Graduate Research
- UMass Chan Cancer Research Team

Additional Resources

New research from the Lodato Lab, published in Nature, reveals an unprecedented map of the molecular changes that occur in the aging human brain.

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The all-day retreat brings together researchers studying diverse aspects of cancer biology and is a private event for the UMass Chan community.

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New research from the Baehrecke lab, published in Nature Structural & Molecular Biology, reveals a targetable mechanism that drives neurodegenerative disease

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MCCB was formed in 2015 from the merger of the Program in Gene Function and Expression and the Department of Cancer Biology.

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The awardees will present their research at the MCCB In-house Seminar on Thursday, September 18th from 12-1 pm in the Paul J. DiMare Center auditorium N1-1100. Please join us in celebrating their accomplishments!

LEARN MORE ABOUT THE AWARDEES

Conducting collaborative, cutting-edge research
to unravel molecular, cellular and genetic mechanisms of disease and translate our discoveries into innovative therapeutic strategies

Research

Explore how our bold discoveries are redefining our understanding of how diseases start and can be treated.

Education

Find out how MCCB equips students and early-career researchers with the skills and knowledge to drive scientific discovery.

Support

Learn more about how you can support MCCB’s fundraising initiatives to advance research at UMass Chan.

MCCB Recognitions & Achievements

Highlights from UMass Chan News

Getting Results…

UMass Chan MD/PhD student Ayush Kumar wins AMA Research Challenge

More than 1,330 research projects were submitted to the 2024 AMA Research Challenge for consideration.

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Recent Publications

Ramirez-Moya et al. The tRNA editing complex ADAT2/3 promotes cancer cell growth and codon-biased mRNA translation. Article | Gregory Lab
Jeffries et al. Single-cell transcriptomics and genomic changes in the ageing human brain. Nature, 2025. Article | Lodato Lab
Murphy et al. MYC and p53 alterations cooperate through VEGF signaling to repress cytotoxic T cell and immunotherapy responses in prostate cancer. Cancer Res, 2025. Article | Ruscetti Lab
Karner et al. GATA3 promotes ferroptosis resistance by repressing integrin β1 signaling. Proc Natl Acad Sci, 2025. Article | Mercurio Lab
Hwang et al. Sphingolipid synthesis maintains nuclear membrane integrity and genome stability during cell division. J Cell Biol, 2025. Article | Torres Lab