Secondary Faculty

Research Interest: The Bosco Lab invesetigates the pathogenic mechanisms associated with neurodegenerative diseases, namely amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) using a multidisciplinary approach.

Research Tools: mammalian cell culture, induced stem cells, M. musculus (mouse)

Broader Impact: ALS, FTD

Office Location: AS6-1057
Phone: 774-455-3745

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Research Interest: The Davis Lab studies how cellular proliferation and inflammation are regulated by JNK signaling.

Research Tools: M. musculus (mouse)

Broader Impact: cancer, cognitive disorders, ischemia, metabolic syndromes, diabetes, non-alcoholic steatohepatitis

Office Location: Two Biotech Suite 309
Phone: 508-856-6054

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Research Interest: The Dekker Lab studies the molecular and biophysical mechanisms of chromosome folding across the tree of life

Research Tools: dinoflagellates, H. sapiens (human)

Office Location: AS5-1049
Phone: 508-856-4371
 
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Research Interest: Dr. Dershwitz studies the clinical pharmacology of intravenous anesthetics and antiemetics.

Office Location: 
Phone: 508-856-2480

Research Interest: The Fazzio Lab works to understand how chromatin structure and its regulators help control transcriptional networks involved in cell fate determination.

Research Tools: cell culture, stem cells, M. musculus (mouse)

Office Location: LRB 519
Phone: 508-856-6014

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Research Interest: Dr. Fuhrmann analyzes the interests and challenges faced by PhD trainees to develop and diseminate effective practices in PhD career development.

Office Location: S1-824
Phone: 508-856-1935

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Research Interest: The Grigorieff lab uses their expertise in physics to advance the field of Cryo-Electron Microscopy.

Research Tools: Cryo-EM

Office Location: AS4-2049
Phone: 774-455-3632

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Research Interest: The Grünwald lab uses advanced single molecule imaging of cell nuclear processes to study nucleocytoplasmic transport in living cells

Research Tools: SMRT microscopy

Office Location: AS4-1043
Phone: 774-455-3632

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Research Interest: Dr. Hayward is a physician-scientist with expertise in muscle gene regulation, ion channel disorders affecting muscle excitability, mechanisms underlying neurodegeneration in ALS, and translational aspects of facioscapulohumeral muscular dystrophy (FSHD), including the establishment of cellular and preclinical models.

Research Tools: M. musculus (mouse), H. sapiens (human)

Broader Impact: facioscapulohumeral muscular dystrophy (FSHD), amyotrophic lateral sclerosis (ALS), periodic paralysis

Office Location: AS6-1045
Phone: 508-856-4147

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Research Interest: The Ip lab studies pathogen-host interactions in the gut with a focus on innate immunity activation and stem cell division.

Research Tools: D. Melanogaster (fruit fly)

Broader Impact: intestinal diseases

Office Location: Two biotech suite 109
Phone: 508-856-5136

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Research Interest: The Benanti Lab studies the molecular mechanisms regulating cell growth and division.

Research Tools: S. cerevisiae (yeast), cell culture (H. sapiens cells)

Broader Impact: Cancer

Office Location: LRB 525
Phone: 508-856-1773

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Research Interest: The Kaufman Lab studies how eukaryotic nuclear organization impacts genome stability and innate immune cell differentiation.

Research Tools: Biochemistry, Molecular and Cell Biology, Genomics

Broader Impact: cancer, infectious disease

Office Location: LRB 506
Phone: 508-856-5016

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Research Interest: The Korostelev Lab studies the structure and function of the ribosome and how it regulates translation in cells ranging from bacteria to neurons.

Research Tools: bacteria, S. cerevisiae (yeast), mammals

Broader Impact: bacterial infections, cystic fibrosis, neurodegenerative diseases (e.g. ALX, FSHD, Fragile-X Syndrome)

Office Location: AS4-2041
Phone: 508-756-2353

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Research Interest: Dr. Koul is interested in neurodevelopmental disorders, molecular biomarkers, and glycolipids.

Research Tools: M. Musculus (mouse), R. Norvegicus (rat), HPLC, Mass spectrometry, proteomics, lipidomics, ELISA.

Broader Impact: Lysosomal disorders, Neurodevelopmental disorders, Multiple sclerosis, Autism.

Office Location: AS3-2155
Phone: 508-856-3072

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Research Interest: The Lambright lab leverages structural biology to study the molecular mechanisms of cell signaling through membrane trafficking.

Office Location: 
Phone: 508-856-6876

Research Interest: The Luban Lab studies HIV replication, pathogenesis and immunity.

Research Tools: HIV-1, ebola virus, SARS-CoV2

Broader Impact: AIDS, viral hemorrhagic fever, COVID-19

Office Location: Two Biotech Suite 219
Phone: 508-856-6899

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Research Interest: The Matijasevic group studies stem cell biology and reprogramming.

Research Tools: M. musculus (mouse)-derived ES cells, H. sapiens (human) induced pluripotent stem cells

Broader Impact: rare diseases

Office Location: S6-117
Phone: 508-856-2459

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Research Interest: The Melikian Lab studies the role of plasma membrane dopamine transporters in synaptic transmission and neuropsychiatric diseases/disorders. 

Research Tools: M. musculus (mouse)

Broader Impact: addiction, autism spectrum disorder, attention-deficit hyperactivity disorder, Parkinson’s disease

Office Location: LRB 726
Phone: 774-455-4308

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Research Interest: The Mitchell Lab studies the emergent properties of the host-drug-microbiome interaction.

Research Tools: E. coli (bacteria), M. musculus (mouse), H. sapiens (human)

Broader Impact: cancer

Office Location: AS5-1045
Phone: 774-455-3795

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Research Interest: Pre-mRNA splicing and its connections to intracellular mRNA localization, translation, and degradation.

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Research Interest: The Munro lab develops and applies quantitative biophysical approaches to visualize virus replication.

Research Tools: single-molecule FRET, fluorescence correlation spectroscopy, molecular dynamics simulation

Broader Impact: Ebola, HIV, influenza, COVID-19, and other respiratory infections

Office Location: AS8-1055
Phone: 774-455-4754
 
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Research Interest: The Peterson lab studies the way chromosome structure influences nuclear processes.

Office Location: Two biotech suite 210
Phone: 508-856-5858

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Research Interest: The Shen Lab utilizes biophysical and biochemical techniques to study amino acid sensing in eukaryotic cells.

Research Tools: cell culture

Broader Impact: cancer, epilepsy

Office Location: Two Biotech Suite 206
Phone: 774-455-6604

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Research Interest: The Song Lab designs smart-fitting synthetic matrices for on-demand biotherapeutics delivery and guided tissue regeneration.

Research Tools: rodents, living polymerizations, shape memory polymers, viscoelastic hydrogels

Broader Impact: traumatic and diabetic bone injuries, osteoarthritis, periprosthetic infections

Office Location: S4-834
Phone:  508-334-7168

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Research Interest: The Stern Lab studies molecular recognition in the immune system, focusing in MHC proteins, T cell receptors, and antigen presentation pathways.

Research Tools: Structural biology including X-ray crystallography, electron microscopy, X-ray / neutron scattering; mass spectrometry and immunoproteomics; mechanistic enzymology, transgenic and stem-cell derived models, T cells.

Broader Impact: Viral infections including influenza, human herpeviruses, and coronaviruses; HLA-lined autoimmune diseases including type 1 diabetes, ankylosing spondylitis, and autoimmune hepatitis.

Office Location: AS0-2051
Phone: 508-856-1831

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Research Interest: The Watts Lab utilizes the tools of nucleic acid chemistry and chemical biology to develop new RNA-based therapeutics.

Research Tools: mammalian cell culture, M. musculus (mouse)

Broader Impact: ALS, Rett Syndrome, Friedreich’s Ataxia, Glioblastoma, Asthma, Pulmonary Fibrosis, Muscular Dystrophy

Office Location: AS4-1051
Phone: 774-455-3784

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Research Interest: The Weng lab applies computation biology methods to analyze large datasets and gain insights into the functions of regulatory elements of the human genome with a particular interest in the role of non-coding variants in human phenotypes and diseases.

Research Tools: computational biology, H. sapiens (human), M. musculus (mouse), D. melanogaster (fruit fly), C. elegans (nematode worm)

Broader Impact: psychiatric and neurological disorders, diseases involving the immune system

Office Location: AS5-1069
Phone: 508-856-8866 

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Research Interest: The Wolfe Lab works on the optimization of genome editing or gene regulation systems for the treatment of monogenic disorders.

Research Tools: CRISPR

Broader Impact: Hematopoietic disorders, muscular dystrophies, Dravet Syndrome

Office Location: LRB 619
Phone: 508-856-3953

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Research Interest: The Zamore Lab studies the biology and biochemistry of Argonaute proteins in animals and bacteria.

Research Tools: D. melanogaster (fruit fly), T. ni (insect), M. musculus (mouse), T. thermophilus (bacteria)

Office Location: AS4-2053
Phone: 508-471-0350

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Research Interest: The Zhong Lab engineers RNA switches and regulatable gene therapies.

Research Tools: rodents

Broader Impact: fatal genetic disease, metabolic disorders, infectious disease

Office Location: LRB 815
Phone: 508-856-1685

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Phone: 508-856-2251
 
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