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About the Lab

The ability of cells to proliferate appropriately and adapt to changing environments is fundamental to development, tissue homeostasis, and human health. Failures in these processes contribute to cancer and numerous other diseases. Our laboratory investigates the molecular mechanisms that control cell proliferation, with a particular focus on how signaling networks regulate protein function, gene expression, and cellular behavior. We seek to understand both how cells execute normal proliferation programs and how they adapt to sustain growth during chronic stress. By combining genetics, functional genomics, and quantitative approaches in yeast and human cells, we uncover fundamental principles of cellular regulation that are broadly relevant to health and disease.

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Recent News 

September 2025: Dynamic phosphorylation of Hcm1 promotes fitness in chronic stress is published in PLoS Genetics
July 2024:
Our paper about calcineurin and the chronic stress response is published in MBoC

July 2024: Linnea Budge and Aurelia Reynolds join the lab as Research Associates 
June 2024: Mackenzie Flynn defends her dissertation. Congratulations Mackenzie! 


Our Affiliations