Aneuploidy, which represents a cellular state of having an abnormal number of chromosomes, is associated with human diseases including mental retardation, neurodegenerative diseases and cancer. Recently, the Torres lab discovered that lipid metabolism is altered by aneuploidy and they investigate the molecular mechanisms that alters lipid synthesis in aneuploid cells. The research from the Torres laboratory will significantly contribute to our understanding how normal cells regulate the levels of, and respond to changes in lipid composition potentially leading to a better rationale for utilizing drugs that target lipid metabolism in the clinic.