Our laboratory studies how steroid hormones control distinct types of cell responses within animal cells and tissues. Researchers in the laboratory combine genetics, genome profiling technologies and proteomics to screen for genes and pathways that control cell survival and cell death. These data are used to develop a comprehensive understanding of the genetic regulatory network that controls cell survival and cell death.

• Lee CY, Clough EA, Yellon P, Teslovich TM, Stephan DA, Baehrecke EH. Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila. Curr Biol. 2003 Feb 18;13(4):350-7. PubMed PMID: 12593803.
• Nelson C, Ambros V, Baehrecke EH. miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2. Mol Cell. 2014 Nov 6;56(3):376-88. PubMed PMID: 25306920; PubMed Central PMCID: PMC4252298.
• Lin L, Rodrigues FSLM, Kary C, Contet A, Logan M, Baxter R, Wood W and Baehrecke EH (2017) Complement-related regulates autophagy in neighboring cells. Cell 2017 Jun 29;170(1):158-171. PMID: 2866617 PubMed Central PMCID: PMC5533186.
• Velentzas PD, Zhang L, Das G, Chang TK, Nelson C, Kobertz WR, Baehrecke EH. The proton-coupled monocarboxylate transporter Hermes is necessary for autophagy during cell death. Dev Cell. 2018 Oct 9: 47:281-293. PMID: 30318245 PubMed Central PMCID: in progress.