The Socolovsky lab has identified several anti-death signaling pathways that are coordinated by the erythropoietin receptor. Together these pathways are responsible for homeostasis and for the stress response in the erythropoietic system.  For more information, see their website.

• Koulnis et al. (2012) Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways. Blood, 119(5):1228-39.
• Porpiglia et al. (2012) Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities. PLoS Biol. 2012 Aug;10(8):e1001383.
• Koulnis M et al. (2014) Erythropoiesis: from molecular pathways to system properties. Adv Exp Med Biol. 844:37-58.