Lawson Lab

The process of organ formation during embryonic development requires the precise integration of many different cellular outputs.  Using the zebrafish as a model system, the Lawson Laboratory investigates how cells coordinate their behaviors during formation of the circulatory system.   Through the application of in vivo time-lapse imaging, along with both forward and genetic approaches, the Lawson Lab has discovered new insights into how blood vessels form in the developing embryo.

  • Siekmann AF and Lawson ND. (2007) Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries.  Nature, 445(7129):781-4. 
  • Nicoli et al.  (2010) MicroRNA-mediated integration of haemodynamics and Vegf signaling during angiogenesis.  Nature, 22;464(7292):1196-200.