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Welcome to the Levitz Lab in the Division of Infectious Diseases and Immunology

Our lab is a part of both the Division of Infectious Diseases and Immunology in the Department of Medicine and the Program In Innate Immunity, an interdisciplinary and interdepartmental group of investigators focused on discovering the underlying mechanisms that drive immune defenses and inflammation.

Our research focus: The immunology of fungal infections

Vaccine development in Cryptococcus neoformans
Identification and epitope mapping of immunoreactive fungal proteins

Representative publications

Wang R, Oliveira LVN, Hester MM, Carlson D, Christensen D, Specht CA, Levitz SM. Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines. PLoS Pathog. 2024 Jul; 20(7):e1012220
Wang R, Oliveira LVN, Lourenco D, Gomez CL, Lee CK, Hester MM, Mou Z, Ostroff GR, Specht CA, Levitz SM. Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases. NPJ Vaccines. 2023 Feb 2;8(1):6.
Specht CA, Homan EJ, Lee CK, Mou Z, Gomez CL, Hester MM, Abraham A, Rus F, Ostroff GR, Levitz SM. 2022. Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles. mBio 13:e03367-21.

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