• Sampling of joints, lungs, kidney for lupus difficult and cause morbidity
• Pancreas in T1D nearly impossible due to volatility of organ, nPOD attempts to solve this by collecting cadaveric organs of limited value to target discovery
• Brain in MS nearly impossible to access in live patients

Solution

Skin is an excellent model organ that is affected by all types of diseases in other organs. It is highly accessible in human patients to analyze cells, signals, disease processes directly ex vivo. The data gathered from skin diseases will be applied as a template to accelerate discoveries in less-accessible organs, which will then support additional progress in a cross-discovery and cross-validation strategies.